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Its role within structured GLP-1 programs reflects a shift away from short-term interventions toward evidence-driven, medically guided metabolic support strategies

A study observed that the number of GLP-1 positive L cells increased after berberine treatment

doi: 10.1001/jamaoncol.2018.3267 351 FinnOJ

Anti-catabolic effect

Studies have shown that some people may have a genetic predisposition to store fat in their abdominal area, leading to a higher risk of developing a bulging belly

In addition, mutations in optineurin (OPTN), an adaptor protein that is involved in autophagy, are associated with glaucoma patients, suggesting a role of autophagy in pathogenesis of glaucoma 26,27